F10 Variants
Factor X (FX) deficiency is caused by variants in the F10 gene, which encodes coagulation Factor X. Compiled within this database are 180 unique variants in the F10 gene, corresponding to 427 individual cases.
Citing Us
Please reference this website by citing the following publications:
- Harris VA, Lin W, Perkins SJ. Analysis of 180 genetic variants in a new interactive FX variant database reveals novel insights into FX deficiency. 2021; 5: e557-e569. DOI PMID: 35059555
- Saunders RE, O'Connell NM, Lee CA, Perry DJ, Perkins SJ. Factor XI deficiency database: an interactive web database of mutations, phenotypes, and structural analysis tools. Hum Mutat. 2005; 26: 192-198. PMID: 16086308
What can you do in this database?
This website enables readers to investigate all pathogenic variants reported in the F10 gene prior to April 2021. The database includes sequence, structural and statistical information on the variants.
Additionally, there is an online form enabling readers to submit new variants and contribute to the genetic services provided by this website.
For easy navigation across the website, please click for the Site Map.
Simple Nucleotide Search
Simple Amino Acid Search
Nomenclature: HGVS & Legacy
Have you or someone you know been diagnosed with Factor X Deficiency?
Latest Release- Version 1.0 (April 2021)
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