In-Depth Variant Analysis:  c.454G>A (p.Ala152Thr)
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c.454G>A
p.Ala152Thr (Legacy AA No. 112)
Variant Type: 
Point
Domain: 
EGF-2
Location: 
Exon 5
Variant Effect: 
Missense
Codon Change: 
G>A
No. of Patients Reported: 
0
Phenotype: 
None
Allele Count *: 
6
Allele Number *: 
282488
Allele Frequency *: 
0.000021
Variant Comments & Reference:
Polymorphism.Residue Information:
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Substitution Analysis:
Structural Implications:
Ala152 is a buried residue  (surface accessibility value = 0 ).
Ala152 is in a random coil area of the FX structure.
The DSSP assignment for this residue is ... C.
Ala152 is in a random coil area of the FX structure.
The DSSP assignment for this residue is ... C.
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