In-Depth Variant Analysis:  c.1222G>A (p.Asp408Asn)
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c.1222G>A
p.Asp408Asn (Legacy AA No. 368)
Variant Type: 
Point
Domain: 
Serine protease
Location: 
Exon 8
Variant Effect: 
Missense
Codon Change: 
G>A
No. of Patients Reported: 
0
Phenotype: 
U
Allele Count *: 
14
Allele Number *: 
282332
Allele Frequency *: 
0.000050
Variant Comments & Reference:
Residue Information:
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Substitution Analysis:
Structural Implications:
Asp408 is an exposed residue  (surface accessibility value = 4 ).
Asp408 is in a region of secondary structure within the FX domains.
The DSSP assignment for this residue is ... S.
Asp408 is in a region of secondary structure within the FX domains.
The DSSP assignment for this residue is ... S.
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