Factor X Variant Database

Terms with a '*' next to them are explained on the Help Page .

c.90G>C

p.Gln30His (Legacy AA No. -11)

Variant Type:

Point

Domain:

Intronic Region

Location:

Variant Effect:

Missense

Codon Change:

G>C

No. of Patients Reported:

Phenotype:

None

Allele Count *:

1147

Allele Number *:

282874

Allele Frequency *:

0.004055

Polymorphism.

Residue Information:

	Name	Type	Cyclic	Size	Position	Hydrophobicity	Charge
Wild Type	Gln	-	acyclic	large	surface	hydrophilic	neutral
Mutated	His	aromatic/basic	cyclic	large	surface	hydrophilic	postive

Grantham Score : 24

PolyPhen-2 Prediction : Benign (SCORE: 0.000)

SIFT Prediction : Tolerated (SCORE: 0.12)

PROVEAN Prediction : Neutral (SCORE: -1.097)

Gln30 is in a region on the surface of the FX structure that is undefined. Hence the FX structure and its JMOL applet are not shown below.

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Factor X Variant Database