In-Depth Variant Analysis:  c.1324G>A (p.Gly442Ser)
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c.1324G>A
p.Gly442Ser (Legacy AA No. 402)
Variant Type: 
Point
Domain: 
Serine protease
Location: 
Exon 8
Variant Effect: 
Missense
Codon Change: 
G>A
No. of Patients Reported: 
0
Phenotype: 
U
Allele Count *: 
-
Allele Number *: 
-
Allele Frequency *: 
-
Variant Comments & Reference:
Legacy cDNA numbering in paper - Leytus et al 1986 (c.1349G>A)Residue Information:
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Substitution Analysis:
Structural Implications:
Gly442 is a buried residue  (surface accessibility value = 1 ).
Gly442 is in a region of secondary structure within the FX domains.
The DSSP assignment for this residue is ... S.
Gly442 is in a region of secondary structure within the FX domains.
The DSSP assignment for this residue is ... S.
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