Factor X Variant Database

Terms with a '*' next to them are explained on the Help Page .

Undefined cDNA (L9P)

p.Leu9Pro (Legacy AA No. -32)

Variant Type:

Point

Domain:

Pre-pro leader

Location:

Exon 1

Variant Effect:

Missense

Codon Change:

No. of Patients Reported:

Phenotype:

Allele Count *:

Allele Number *:

Allele Frequency *:

Residue Information:

	Name	Type	Cyclic	Size	Position	Hydrophobicity	Charge
Wild Type	Leu	aliphatic	acyclic	large	buried	hydrophobic	neutral
Mutated	Pro	-	cyclic	medium	surface	hydrophobic	neutral

Grantham Score : 98

PolyPhen-2 Prediction : Probably Damaging (SCORE: 1.000)

SIFT Prediction : Probably Damaging (SCORE: 0.00)

PROVEAN Prediction : Deleterious (SCORE: -2.807)

Leu9 is in a region on the surface of the FX structure that is undefined. Hence the FX structure and its JMOL applet are not shown below.

NOTE: If no Java applet appears or a Java error message is shown, please click the following LINK.

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Factor X Variant Database